Word: ipse
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A year later, Yamanaka followed up his work by reporting success with the same four factors in turning back the clock on human skin cells. At about the same time, in Wisconsin, Thomson achieved the same feat using a different cocktail of genes. With those studies, what became known as...
Beyond Stem Cells Melton, for one, isn't wasting any time before running through those doors. The iPS technology is the ultimate manufacturing process for cells; it is now possible for researchers to churn out unlimited quantities of a patient's stem cells, which can then be turned into any...
Before that can happen, however, Melton wants to learn more about how diseases develop. And iPS cells make that possible too. For the very first time, he can watch Type 1 diabetes unfold in a petri dish as a patient's cells develop from their embryonic state into mature pancreatic...
The next step, according to lead author Danwei Huangfu, will be to find a combination of chemicals that can replace the remaining two genes needed to create iPS cells.
Matthias Stadtfeld, the lead author for Hochedlinger’s paper on the use of harmless adenoviruses, cautioned that the efficiency of producing iPS cells using this method is “already very, very low.”