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...That's exactly what anti-HIV drugs, known as antiretrovirals (ARVs), are designed to do: interrupt the virus at various points along its nefarious journey. The FDA has approved four different classes of ARVs, each of which blocks a separate step in HIV's life cycle. The strategy is to build up a security detail of pharmacological agents that together thwart the virus at every turn, making sure that every receptor, protein and enzyme that the virus co-opts to sneak into a cell is covered...

Author: /time Magazine | Title: Beefing Up the Arsenal Against AIDS | 3/2/2007 | See Source »

...going to survive the Cultural Revolution, I needed physical and mental exercise. I devised a series of exercises that moved every part of my body from my head to my toes; I did this twice a day. At first, the exercise exhausted me, and I had to interrupt it with frequent rest. Also I had to avoid the prying eyes of the guards, as exercise other than a few minutes of walking in the cell after meals was forbidden. Nevertheless, I managed to exercise each day and after a few months I recovered my physical strength somewhat, as well...

Author: /time Magazine | Title: Life and Death in Shanghai | 2/5/2007 | See Source »

...Mexico. ''I want to be Jewish. I don't have to apologize. It is my very essence.'' He is an affectionate and demonstrative father, and small children tend to sprawl on his knees and interrupt him with coy, lolling, attention-seeking questions. He pauses during his interview every time to answer the child first. Palestinians? ''There is no Palestine.'' Jews called it Palestine before 1948. The Arabs who call themselves Palestinians are transients. West Bank? ''There is no West Bank in real geography. It is really the west bank of the Dead Sea.'' Dayan does not ''want to offer Arabs...

Author: /time Magazine | Title: ISRAEL At 40: the Dream Confronts Palestinian Fury | 2/5/2007 | See Source »

Devotees of filing often interrupt their thought flow to stuff papers in folders, while pack rats just toss papers to the side for later. Procrastination like that can actually pay off. "Putting off undertaking almost any form of neatening or organizing will probably have some advantage," write Abrahamson and Freedman, "because it's much more efficient to organize a large set of things at one shot than it is to try to organize them in pieces as they come along...

Author: /time Magazine | Title: Messy is the New Neat | 1/18/2007 | See Source »

...vulgarity (there are fart jokes) with a screen-goddess glamour that can't be faked. "Pedro says I have a dark side," Cruz says, "and I know he does. Maybe that's another thing that connects us. I never feel completely safe next to him." Almodóvar and Cruz interrupt each other constantly, sometimes in Spanish, sometimes in English. "I feel like a couple who are friends, but they could be more," Almodóvar says. "They are in that level where they can go another step. It can go on forever...

Author: /time Magazine | Title: How Pedro Rescued Penelope | 11/12/2006 | See Source »

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