Word: humanize
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Dates: during 2000-2000
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Thanks to technologies spawned by genomics, the list of potential drug targets is growing rapidly. Human Genome Sciences and Seattle-based ZymoGenetics, for instance, are independently developing drugs to inhibit a newly discovered factor that stimulates B cells and is produced copiously in RA and lupus patients...
Glivec is just one of several new therapies that work by cutting a cancer cell’s lines of communication, either preventing it from reproducing or forcing it to self-destruct. Other signal-jamming treatments use monoclonal antibodies, tiny proteins that resemble the human immune system’s own antibodies but which bind to the surface of cancer cells. New York-based ImClone Systems has an antibody called IMC-C225, now in the final phases of testing in colorectal and head and neck cancer, that acts like bubble gum stuffed in a keyhole. It prevents a specialized protein known...
...pharmacological, Parkinson’s patients have tried over the years to control the tremors, rigidity and other symptons that characterize the disease. All of the treatments offer some relief, but none can remotely be called a cure. Now that may be changing. The deeper scientists peer into the human genome, the more they’re uncovering the secrets of Parkinson’s-and the more they’re growing convinced that next-generation drugs may be at last be able to beat back the disease. What’s more, the benefits may not be limited to Parkinson...
...dopamine neurons. The tricky part is that most trophic molecules are too big to cross the blood-brain barrier, so Guilford and Amgen are working on a smaller one that can get where it needs to go. The progress so far is promising. "We’re in phase two human trials and the study is going very well," says Dr. Craig Smith, an M.D. and the president of Guilford. "If the drug proves safe and extremely effective in trials, it could be on the market as early...
...result. But the laws were there to regulate it. And under the law, George Bush won Florida. This is not to say that he won in the sense of cosmic certainty, under the aspect of eternity, in the sight of an all-knowing being. Cosmic certainty is denied to human beings. In its place--a poor substitute, I admit--they have laws...