Word: gewirtz
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...growing body of research suggests there's another, less visible reason to focus on your gut if you want to lose weight. Scientists led by Andrew Gewirtz at Emory University reveal that your intestines harbor a universe of bacteria - the so-called gut microbiota - that may play an important role in whether your body will store the food you eat as extra pounds. (See pictures of what the world eats...
...Gewirtz's team, including researchers at Emory, Cornell University and the University of Colorado at Boulder, became intrigued by the relationship between gut bugs and weight when they noticed that lab mice lacking a certain protein had more of the bugs than other animals and were about 15% heavier. These mice also had a higher level of inflammation, which the authors explain in their paper published online Thursday in Science Express is what may account for the extra weight. Inflammatory signaling can promote a condition called metabolic syndrome, which causes weight gain, high blood pressure and high cholesterol levels...
...fatter mice in Gewirtz's study had been bred to lack a protein known as toll-like receptor 5 (TLR5), which most intestinal cells sprout on their surface. Its job is to recognize and bind to the whiplike flagella that bacteria use to move around. TLR5 acts as a traffic cop for controlling the mass of pathogens living in the intestine; without it, the normally harmless gut bacteria tend to overflourish and expand in number. (See and listen to an audio slideshow about obesity rehab...
...Julian B. Gewirtz...
...original script, by Russell Gewirtz (Inside Man), actually has an idea that hasn't been truncheoned to death in a zillion other movies: What if a cop were a serial killer? A peace officer certainly has motive, means and opportunity to knock off a dozen or so malefactors who probably deserve to die but have escaped conviction. The cop could truly believe that killing them is nothing less than righteous. He might think of himself as De Niro's Travis Bickle did in Taxi Driver, using his gun to wash the New York streets clean of their wretched refuse...