Word: geneses
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Completeness and accuracy were the Human Genome Project's twin mantras from its formal start in 1990. At that point, researchers had already painstakingly identified more than 4,000 of the 100,000 genes that serve as the blueprint for a functioning human being--each gene carrying instructions that tell...
But while the genome project has been methodically chronicling the details of human cells--including long stretches of DNA, amounting to some 97% of the total, that contain no genes at all--private companies have opted for a very different approach. Their maps are more like satellite photographs that take...
Scott's rivals at Genset, based in France, are taking a similar approach: their map, to be completed in early 2000, will highlight just 60,000 of some 10 million biochemical "beacons" found along the human genome. By comparing the DNA of many individuals in and around these signposts, Genset...
Venter's reputation as a creative thinker was made back in the late 1980s. He was studying genes at the National Institutes of Health when he came to a humbling realization: while the greatest minds in biochemistry still hadn't figured out how to locate a gene efficiently, cells do...
Decoded cDNA began tumbling out of his machine. A portion of these decoded regions were used as tags--he called them expressed sequence tags (ESTs)--to help scientists distinguish one gene from another and identify related genes even in other species. "His invention of ESTs was inspired," says Victor McKusick...