Word: geneses
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“We can now find genes that protect against certain diseases and look into increasing expression of these [genes] as drug therapy,” she said.
Sabeti and her team have already used the LRH test to identify the positive selection of two genes associated with resistance to malaria, a life-threatening parasitic disease transmitted by mosquitoes.
Gene combinations containing two forms of genes that offer partial protection against malaria were found to be statistically common in African populations but absent in populations outside the continent.
The LRH test assesses the ages of gene combinations by measuring their association with nearby genes, which decreases with time. This measurement is known as a linkage disequilibrium.
During the 1970s, the three began studying the genetics of C. elegans, a tiny worm. They eventually found that a specific set of genes tells cells when to die as part of the worm?s normal growth and development - and later, those same genes were found to exist in the...