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Those genes hardly exhaust the list of possibilities. Among the suspects are virtually all the genes that control brain development and perhaps cholesterol and immune-system function as well. Christopher Stodgell, a developmental toxicologist at New York's University of Rochester, observes that the process that sets up the brain...

Author: /time Magazine | Title: The Secrets of Autism | 5/6/2002 | See Source »

A proliferation of connections between billions of neurons occurs in all children, of course. A child's brain, unlike a computer, does not come into the world with its circuitry hard-wired. It must set up its circuits in response to a sequence of experiences and then solder them together...

Author: /time Magazine | Title: The Secrets of Autism | 5/6/2002 | See Source »

Currently Courchesne and his colleagues are looking very closely at specific genes that might be involved. Of particular interest are the genes encoding four brain-growth regulators that have been found in newborns who go on to develop mental retardation or autism. Among these compounds, as National Institutes of Health...

Author: /time Magazine | Title: The Secrets of Autism | 5/6/2002 | See Source »

The genes that set the stage for autistic disorders could derail developing brains in a number of ways. They could encode harmful mutations like those responsible for single-gene disorders--cystic fibrosis, for instance, or Huntington's disease. They could equally well be garden-variety variants of normal genes that...

Author: /time Magazine | Title: The Secrets of Autism | 5/6/2002 | See Source »

In the end, it is not merely possible but likely that scientists will discover multiple routes--some rare, some common; some purely genetic, some not--that lead to similar end points. And when they do, new ideas for how to prevent or correct autism may quickly materialize. A decade from...

Author: /time Magazine | Title: The Secrets of Autism | 5/6/2002 | See Source »

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