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...knowledge of the precise immune factors, or correlates, that prevent infection, testing any vaccine candidate that functions by triggering immune defenses would be guesswork. That's why, Fauci says, he rejected the proposal to do a large trial, involving thousands of patients and numerous immune correlates. "What I will entertain is a leaner, meaner and smaller trial that precisely asks and answers, 'Does the vaccine work and is it successful in lowering viral load?'" Fauci says. "If it does, then we go back and start investing more money, people and samples to see if we can find the right immunological...

Author: /time Magazine | Title: What's Next for the HIV Vaccine? | 7/19/2008 | See Source »

...past decade Leith - lying two miles (3.2 km) northeast of the city center - has experienced a rapid renaissance thanks to the closure of the docks and the cleaning up of once polluted waterways. The addicts have been replaced by white-collar workers, who live in waterside lofts and entertain themselves at the many galleries and restaurants that have arisen...

Author: /time Magazine | Title: On the Waterfront | 6/12/2008 | See Source »

...much more obesogenic, or obesity-supporting. Think of the ever increasing supply of fast-food outlets, where meal sizes have ballooned, or the fact that simple physical activity has been largely eliminated from the daily lives of children, who ride in cars where their grandparents might have walked and entertain themselves with an array of sedentary electronic pastimes that didn't even exist a generation ago. It shouldn't be surprising that many overfed, underactive kids lose the battle with their weight. "The environmental factors are much more compelling toward obesity than they were 30 years ago," says William Dietz...

Author: /time Magazine | Title: It's Not Just Genetics | 6/12/2008 | See Source »

...between the Allston-Harvard Task Force and Harvard Construction Mitigation website to limit the days construction will continue past 6 p.m. Harvard has also expressed support for a measure to provide an after–school tutoring and lecture program to Allston children; in this vein, Harvard ought to entertain the possibility of opening a University affiliated high-school in Allston. We hope that in addition to these steps, Harvard will open its shuttles to residents, create plenty of green spaces, and give the Allston community access to the planned art museum...

Author: By The Crimson Staff | Title: Building for Today and Tomorrow | 6/3/2008 | See Source »

...advent of Spring again reminds us of the unfortunate scheduling of weekday parietal hours. While our natural inclinations would send us down to the playing fields to help the House athletic teams or out into the sun for various Mithraic rites, we are forced to entertain lady guests in our rooms during daylight hours...

Author: By The Crimson Staff | Title: Love in the Afternoon | 6/2/2008 | See Source »

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