Word: drugging
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...Breast cancer is the model for treating cancer as a chronic disease, largely because it's the focus of so much research and drug development. "We have a ton of drugs that work for breast cancer - eight or nine - more than for any other cancer," says Dr. Christy Russell, co-director of the Norris Breast Center at the University of Southern California. The approach for someone with metastatic disease like Elizabeth Edwards, says Russell, is to use a drug until it stops working - as it almost inevitably will - and then switch to something else, possibly buying years of relatively good...
...Researchers have wrung other kinds of information out of cancer cells, including the way they spur the formation of blood vessels, which nourish their growth. Avastin, approved in 2004, is the first drug to throw a wrench into the process by suppressing a tumor's ability to recruit vascular growth factors. As with many of the newer therapies, doctors have found that it works best as part of a cocktail of cancer drugs...
...chemotherapy will be helpful for early breast cancer patients with recent diagnoses. At Duke University, molecular geneticist Joseph Nevins is testing a similar gene-based test for lung cancer. Researchers are aiming for tools that will tell them not only whether chemo is needed but also which specific drugs to use. Such a screen already exists for Herceptin, and many others are in development. Meantime, at the M.D. Anderson Cancer Center in Houston, Dr. Roy Herbst, chief of thoracic medical oncology, is looking for protein markers on lung tumors that will enable doctors to make the best choice among four...
...Fortunately, patients like Snow have more options today than ever. Until 10 years ago, there was only one drug, a chemotherapy agent, available to treat colon cancer, and it wasn't very effective. In the past decade, more chemotherapy drugs, which are easier on the body, and new classes of targeted therapies, which specifically block a tumor's ability to recruit growth factors and blood vessels, have improved the survival of patients...
...Nexus of Terrorism and Drugs The Noorzai case [Feb. 19] is a perfect example of this Administration's botched war on terrorism and the Drug Enforcement Administration's handling of the incredibly stupid war on drugs. Haji Bashar Noorzai could have been a real asset in rooting out the Taliban. Intelligence on the ground is a most valuable resource. Has Noorzai's arrest really made a difference in heroin production? U.S. taxpayers will now have to spend millions to prosecute and detain him. The U.S. could wipe out the drug trade tomorrow by legalization and taxation, which would take away...