Word: drugging
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After nearly two years of waiting, the results came out on Monday on the long-awaited heart drug Vytorin - and the news wasn't good. Vytorin's manufacturers, Merck and Schering-Plough, announced that while the drug reduced levels of LDL, or bad cholesterol, in a group of 750 patients, the medication, which has been on the market since 2004, had little effect on the buildup of plaque in the arteries, a harbinger of heart attack and stroke...
...ENHANCE was never designed to provide outcomes, meaning the prevention of major adverse cardiovascular events such as heart attack or stroke," says Davies. "This was an interesting scientific exercise to look at the impact of the drug on plaque, which is itself a surrogate end point for these events...
ENHANCE may only be the opening salvo against Vytorin - three larger trials are currently under way to measure the drug's effect on heart attack and stroke - and many physicians are not optimistic. "Given these results, it's highly unlikely that those outcomes studies will show dramatic benefit for Vytorin," notes Dr. Raymond Gibbons of the Mayo Clinic, and past president of the American Heart Association...
...evidenced by the Mitchell Report, baseball is no longer in denial about its performance-enhancing drug problem. Back in 2005, Mark McGwire's low moment - "I'm not here to talk about the past" - shed light on the steroid issue, and forced baseball to act. But trying to shame, or even vindicate, Roger Clemens a month later? How does that reform the game...
...their various lieutenants and seconds trying to "help" explain things, which almost always makes things worse. That much was clear over the weekend, when BET founder Bob Johnson, in trying to defend the Clintons, appeared to all the world to be bringing up Obama's admitted history of drug use (Johnson later claimed he was actually referring to Obama's history as a community organizer, a laughable explanation that only dug the hole deeper...