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...under official seal. On Aug. 24, the Los Angeles Times reported that the L.A. County Coroner's Office found fatal amounts of the powerful anesthetic (also known as Diprivan) in Jackson's body. The information was contained in a search warrant for the office of Jackson's personal physician Dr. Conrad Murray that was unsealed in Houston, where Murray has an office. According to the Times, Murray told police that he had been administering 50 milligrams of propofol to Jackson intravenously every night for six weeks to treat insomnia. But according to the report, Murray said he was afraid Jackson...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

Jackson's death on June 25 has brought the subject of propofol abuse from obscure medical research papers to the celebrity-laden Web pages of TMZ. Until Jackson's death, there was little talk about it in celebrity circles. "I didn't know much about it," says Chopra. Dr. Drew Pinsky, host of Celebrity Rehab, says he had never seen the drug abused by his hard-living Hollywood clientele. Home use of Diprivan "is something I had never heard of," Pinsky tells TIME. "I'd have an easier time believing that Martians had set down outside this building...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

...Dr. Paul H. Earley, medical director at Atlanta's Talbott Recovery Campus, equates abusing the drug to playing Russian roulette. "There is a very narrow window to go from feeling euphoric to be being unconscious to being unconscious and not breathing," says Earley. In a closely monitored operating theater, doctors can make quick adjustments to avoid problems. Abusers have no such recourse for a drug that acts so quickly that they often injure themselves immediately by falling. Earley says that a center that specializes in drug abuse among medical professionals started to see early signs of propofol abuse five years...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

Though the attention around the previously obscure drug has increased awareness of its dangers, there is also the chance it will raise curiosity among potential abusers. Dr. David Sack, chief executive officer of Promises rehabilitation facility in Malibu, Calif., says the drug presents inherent obstacles to mainstream appeal, including its lack of street availability and its need to be administered by a needle. While Hollywood's troubled abusers have yet to start showing up at his doors with propofol problems, he doesn't rule it out. "Whenever a drug gets attention like this in the media, people want...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

Your cover story "Paging Dr. Obama" was timely [Aug. 10]. Unfortunately, the President's plan misses a fundamental point. Our flawed legal system is largely responsible for the way doctors defensively practice medicine and the pharmaceutical and insurance companies and hospitals gouge consumers unlike anywhere else in the world. Nowhere else are there as many malpractice suits as in the U.S. Shame on the lawyers who load the judicial system with phony lawsuits. Without appropriate malpractice reform, nothing will improve. Sudhir K. Bhaskar, ORLANDO...

Author: /time Magazine | Title: Inbox | 8/24/2009 | See Source »

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