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...antibiotics have side effects, but fluoroquinolones--the family that includes Cipro--have had more than their share of strange ones. Earlier generations of the drugs caused personality changes, cardiovascular complications and ruptured tendons, particularly the Achilles tendon, in a small number of users. Three earlier fluoroquinolones had to be taken off the market. One, Omniflox, was withdrawn after only three months, following dozens of severe reactions, including several deaths...

Author: /time Magazine | Title: Cipro to Doxy: Why the Switch? | 11/5/2001 | See Source »

Doctors stress that the side effects of Cipro, one of the newest fluoroquinolones, are no worse than those of penicillin and tetracyclines. Common complaints associated with the drug are nausea, diarrhea and vomiting. About 3% of patients in clinical trials had to stop taking it because of stomach pain, skin rashes, lightheadedness or headache. Fewer than 1% experienced the more severe events, including the torn tendons, hallucinations and seizures...

Author: /time Magazine | Title: Cipro to Doxy: Why the Switch? | 11/5/2001 | See Source »

Even under the best circumstances, Cipro is not an easy pill to swallow. Dairy products interfere with the drug's absorption, so you need to wait at least two hours before drinking milk or eating yogurt or cheese. Cipro also increases sensitivity to the sun, so to avoid a rash, you need to cover exposed skin when going outdoors...

Author: /time Magazine | Title: Cipro to Doxy: Why the Switch? | 11/5/2001 | See Source »

...colorful poster from Mrs. Mehedin's first-grade class at Wilson Elementary. It shows 13 hand-colored "awards," each thanking Gilmore for providing the community of about 90,000 with parks, snowplows, garbage collection and the like. Soon the poster may have to be updated: THANK YOU FOR THE CIPRO...

Author: /time Magazine | Title: Behind The Trenton Postmark: A Town's Take-Charge Attitude | 11/5/2001 | See Source »

...confirmed that two New Jersey postal workers, one from Hamilton, had been infected with anthrax. Gilmore knew from sources at Hamilton's Robert Wood Johnson University Hospital that there was not enough Cipro on hand to treat hundreds of postal workers and that many area pharmacies had run out. When he found out that state officials were planning to advise all Hamilton postal workers to contact their doctors and seek antibiotics, he was appalled. "The decision is made that they have to start a seven-day prescription of Cipro to maybe save their lives," he said. "But they're told...

Author: /time Magazine | Title: Behind The Trenton Postmark: A Town's Take-Charge Attitude | 11/5/2001 | See Source »

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