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After plodding along at a snail's pace over the past five years, stem-cell research-at least the scientific side of it-took a few bold steps forward Wednesday. As Congress gets set to vote on legislation that would expand federal funding for the field to include studies on excess IVF embryos, researchers in the U.S. and Japan announced exciting advances in their ability to turn back the clock on older, adult cells and get them to generate embryonic stem cells. The findings could expand the ways that doctors and patients eventually generate customized stem cells for treatments...
...work, published in the journals Nature and Cell Stem Cell, represent true milestones, not only in the field of stem-cell research, but in the broader discipline of early biological development. Led by Shinya Yamanaka at Kyoto University, one group successfully coaxed a mouse skin cell to reverse its development and return to an embryonic stage at which it produced stem cells. Two other groups, based at Harvard Stem Cell Institute (HSCI) and the Whitehead Institute for Biomedical Research at MIT, obtained similar results working independently. In the final paper, Kevin Eggan, also at HSCI, showed that even fertilized mouse...
...American citizens assemble at the southern border bearing arms. What do you say? -Richard D. Coburn, DenverAssembling on the border is a fine idea. Guns are probably not necessary because, as the Minutemen were able to show, you can accomplish the same goal-reducing the flow of illegals-with cell phones, binoculars and lawn chairs...
...everyone is convinced that banking stem cells this way would be providing a truly valuable medical service. "Given the current status of the research and the many innovations that are likely down the road," says Dr. Renee Reijo Pera, director of Stanford University's Human Embryonic Stem Cell Research Center, "the value of this service is minimal, especially in light of the the difficulties with cryopreservation...
...Krtolica maintains that the frozen embryos StemLifeLine starts out with are only slightly less viable than fresh ones in generating stem cells lines, and that freezing cells is a routine and well understood process. So far, she says, there is no evidence that frozen stem cell lines are any less active or viable when thawed - but scientists don't yet have a lot of experience in manipulating and storing human stem cells. The most harmful part of the process, says Krtolica, is the freezing itself; "the freezing process has the biggest harm in killing cells," she says. "The number...