Word: bloodstream
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Dates: during 1980-1989
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...pair spent much of the 1970s painstakingly deciphering how the body regulates cholesterol levels. Just as oil and water cannot mix without a detergent, cholesterol cannot enter the bloodstream unless it is ferried within a complex of molecules called low-density lipoprotein, or LDL. The Texas researchers found that the LDL ferries travel to docks called LDL receptors. More important, they learned that low cholesterol levels in the liver trigger the production of more receptors, which pull LDL out of the blood. But if the liver does not make enough receptors, the LDL levels in the blood will rise...
...researcher, they tried it in 1982 on six patients. Within a few weeks, blood-cholesterol levels had dropped from an average of 350 to 250. Furthermore, the drug actually boosted the amount of high-density lipoprotein (HDL), a natural substance that seems to scavenge excess cholesterol out of the bloodstream. "That study really opened people's eyes," recalls Grundy...
...Through his bloodstream Tuck does swerve...
...center of all the attention is a class of compounds known as sucrose polyester (SPE). Although that may sound like a new material for leisure suits, SPE looks and tastes like vegetable oil but passes through the body without entering the bloodstream. Research at the University of Cincinnati appears to show that it can reduce a person's existing cholesterol levels. It supposedly satisfies what market researchers call the "mouth-feel" requirement that eludes so many yucky-tasting diet-oriented products. P&G, which has tested olestra on more than 1,800 people in the past 15 years, contends that...
Previous research has indicated that alcohol consumption reduces the risk of heart disease by reducing the amount of one type of cholesterol in the bloodstream. But with the results of the new study, Colditz said, "We're left with the trade...