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...cannot grow much beyond the size of a peppercorn without an ever-expanding network of blood vessels. Clinicians are now testing more than a dozen treatments aimed at halting that process, including some old-line drugs that have turned out to have anti-angiogenic properties. Thalidomide, which caused devastating birth defects in some 12,000 children worldwide before it was withdrawn in the early 1960s, is finding a new lease on life against multiple myeloma and liver cancers. Pharmaceutical giant Bristol-Myers Squibb is testing an antiangiogenic drug that was initially developed to keep cancer from worming its way into...
Major life changes such as marriage, divorce, birth, illness or death can trigger a separation, Netzer says, but usually only if tensions have been building for years. Consider, for example, the case of Michael Carr, 42, a money manager, and his older brother Steven, who ended contact with each other two years ago. When they were growing up, Michael saw Steven, two years older, as his best friend and guardian angel. "We were really close," Michael says. "He was the ringleader in the neighborhood. He was my hero." (Steven did not respond to requests for an interview...
...When you look at what legislation is considered ripe for bipartisan compromise, the two parties are split: The Democrats talk about coming together on campaign finance reform and a patients' bill of rights, while the Republicans want to focus on abolishing the estate tax or a ban on partial birth abortion." All issues that have garnered significant bipartisan support in the past - but not exactly the legislative trifles one might expect an evenly split Congress to tackle right...
...while Shaggy and Scooby's (Zoinks!) belief in the supernatural was always exposed as folly. Other myths of childhood had evaporated before my eyes. The idea of storks delivering children, a notion I was never that vehement about but was certainly familiar with, exploded with the decidedly non-avian birth of my sister. As I learned the standard magic card tricks that would only excite wonder in sympathetic adults or gullible children, the familiar mantra that "it's just a trick, there is no magic" began to grow in credibility...
...undeniably built on foundations that I reject. For me the holiday will always be tied to questioning, to the evaluation of evidence, both of Santa and God, but more generally the physical world. Luckily, a figure emblematic of just this sort of material exploration has a convenient date of birth. Sir Isaac Newton was born on December...