Word: beyond
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Dates: during 2000-2000
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...Beyond that, things get murky. It's not yet clear, for example, when tau enters the picture. Up to now, most thought the tangles form much later than the plaques. But neuroscientist Peter Davies of Albert Einstein College of Medicine thinks this view will be proved wrong. He believes some still unidentified biochemical event precedes the formation of tangles and plaques, perhaps a malfunction in the machinery that puts proteins together. "The question from the therapeutic standpoint," he observes, "is, What's responsible for the symptoms of disease? What's killing the cells? Is it amyloid...
...BEYOND BETA AMYLOID...
...mystery: Why do we shun our pedaling heroes? The only explanation I can come up with is that we're just intimidated by the whole cycling world. The physical and mental stamina required to win a Tour is worlds beyond anything demanded in traditional American sports (which may be why Americans are so put out by cycling - most of us realize we can never, ever be that fit, and it makes us vaguely uncomfortable). So we go back to our putting greens and swinging our little metal sticks, and avoid contemplation of our inadequacies...
...slot of a song that not only was not a hit, but has rarely if ever been covered by anyone else: The John Lennon autobiographical reverie "In My Life," from the Beatles' "Rubber Soul," widely considered to be one of the Fab Four's first forays beyond standard boy-girl preoccupations. As if to counterbalance Lennon's contribution, "Here, There and Everywhere" comes in at number four, its killer modulation a reminder that as the two composers diverged (in spite of the pro forma "Lennon/McCartney" credit), McCartney did more than just hold his own, and was probably the superior melodist...
...Nature magazine underlining the urgency of curbing the spread of HIV as the priority in the fight against AIDS. The declaration concurs that economic factors such as malnutrition make those infected more prone to the rapid onset of AIDS following HIV infection, and also that poverty puts lifesaving treatments beyond the means of the overwhelming majority of those infected. But it stresses that "none of these factors weakens the scientific evidence that HIV is the sole cause of the AIDS epidemic...