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Before they can effectively combat the bacteria that may infect a patient, threaten a swiftly spreading epidemic, or contaminate a municipal water sup ply, doctors and scientists need quick and positive identification of the invading organisms. But traditional laboratory tests that single out and classify bacterial troublemakers are complex, time-consuming and sometimes inconclusive. Often, before the results are in, the disease has spread or the patient has died. In the future, though, bacteria may lose their cloak of anonymity more quickly. Scientists have discovered that each species and strain has a distinctive "fingerprint" that can be used for virtu...

Author: /time Magazine | Title: Biochemistry: Fingerprinting Bacteria | 7/1/1966 | See Source »

...tests involving 32 different strains of bacteria, Cornell University Biologist Martin Alexander and General Electric Chemist John Gould have found that each excretes metabolic wastes that are chemically distinct. When the waste products of a single strain are passed through a laboratory chromatograph. a device that separates chemical compounds, they produce a distinctive graph with characteristic peaks and valleys. Thus the graphs or chromatograms of unidentified bacteria can be com pared with those of known bacteria and-like fingerprints-be used to establish their exact identity...

Author: /time Magazine | Title: Biochemistry: Fingerprinting Bacteria | 7/1/1966 | See Source »

Segregated Compounds. To prepare a bacterial chromatogram, Scientists Alexander and Gould use a pure strain of bacteria, allow them to grow for several hours in a nutrient solution, then extract the metabolic products that have been excreted. These are injected into a chromatograph, where they are converted by heat into gaseous form and fed into a column containing a packing material and an organic liquid such as Carbowax-a chemical that has a different attraction for the molecules of each chemical compound. Thus every compound that passes through the column is slowed to a degree...

Author: /time Magazine | Title: Biochemistry: Fingerprinting Bacteria | 7/1/1966 | See Source »

...paper to be published in June. Mario R. Capecchi says that in a typical bacteria. E. coli, one special amino acid is probably required to initiate the synthesis of all proteins. He suggests that this some amino acid may be necessary for the initiation of all protein synthesis...

Author: By Mark L. Rosenberg, | Title: Bio Students Make Genetic Breakthrough | 5/11/1966 | See Source »

Diet & Stress. In treating acne, Dr. Fisher prescribes antibiotics to keep down the bacteria, and drains the pustules. He condemns the acne victim's bathroom ritual of pimple-squeezing as dangerous and likely to spread the infection. Dr. Fisher prescribes drying lotions to reduce the skin's oiliness, and he preaches the importance of soap-and-water cleanliness, plus germicides...

Author: /time Magazine | Title: Dermatology: Acne, Hormones & Milk | 4/29/1966 | See Source »

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