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...separate area of research, Xie at Massachusetts General tested another anesthetic, isoflurane, on a culture of human brain cells. (Isoflurane had already been shown to cause cognitive impairment in rats.) He saw a vicious cycle of apoptosis and the accumulation of beta-amyloid protein - the sticky plaques that build up in Alzheimer's patients' brains - among the cells. But in this case, it may have been an excess of calcium that led to cell death. Xie and his colleagues have since found that the Alzheimer's drug memantine, which works by reducing calcium levels inside cells, can slow the rate...
...Whether these two areas of research are related was a topic of debate at the annual convention of the American Society of Anesthesiologists (ASA) in New Orleans in late October. So too was their clinical significance. No population study has ever conclusively linked anesthetic drugs to Alzheimer's or dementia. (Although doctors have long noted that about 10% of patients who receive anesthetics for major surgery experience a temporary period of "post-operative cognitive decline" after coming out of anesthesia, the condition is not limited to elderly patients, and it could be the result of inflammation or other stress responses...
...dirty work. Following a personal plea from Rudd last month, Indonesian President Susilo Bambang Yudhoyono gave the Oceanic Viking the green light to disembark in Indonesia. It was taken to Bintan Island, where an Australian-funded detention center was awaiting the refugees. But on its arrival, Ismeth Abdullah, the area governor, told the press that his province was not "a dumping ground" for the asylum seekers and would not allow the ship to off-load. He later said that the island would accept the refugees provided they didn't stay longer than a month. The asylum seekers, for their part...
...given the ship until Nov. 6 to leave international waters. No country wants the public relations nightmare of physically forcing the refugees from the boat. Indonesia lays the responsibility squarely on Australia's shoulders, and Australia says the refugees, who were found in Indonesia's search-and-rescue area, are Indonesia's problem. "I think the government foolishly created an embarrassing situation for itself," said Lindy Edwards, a political scientist at the Australian National University. "They have gone and generated the standoff that they can't back down." The 255 refugees on the ship in Merak are also stuck...
...grows more divided between urging a peaceful solution and a full military intervention. Some have speculated the stalemate could mean political fallout for the relatively new Prime Minister, but Rudd told reporters in Townsville on Nov. 2 that he plans to stay the course. "This is a very hard area for government, but our job is to implement a responsible policy in the national interest," he said. It's just unclear which part of the nation he is referring...