Word: acth
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...federal government recently granted $61,000 to the University and $89,000 to the Medical School for research in blood separation, purification, and storage, and in synthesized acth and cortisone, two hormone extracts...
Pregnenolone. Some doctors reported that half of their arthritis patients were helped by pregnenolone. Some said they got no results at all. Pregnenolone's great advantage: it does not have the unpleasant "side effects" of cortisone and ACTH, its leading rivals in the treatment of arthritis. It is also cheaper and is available in large amounts...
...your Dec. 18 medicine story "From the Discard" you state that diabetes and hardening of the arteries are generally encountered as complications of ACTH treatment. A temporary metabolic derangement resembling diabetes mellitus is occasionally (but by no means always) encountered following the administration of large amounts of ACTH, but the condition subsides when the hormone is stopped...
...hardening of the arteries, there may be some connection to pituitary and adrenal function, but there is no clear evidence that ACTH therapy, as it is administered, either produces or aggravates the condition. I call this error to your attention because it would be a pity if patients receiving ACTH were unnecessarily frightened by your report...
Among the 100 papers read at Chicago last week giving details of experiments in ACTH during the past year, there were other evidences of the drug's usefulness in short-term applications. In Savannah ACTH had saved one woman from the bite of a black widow spider and another from the bite of a copperhead snake. Early administration of ACTH in some cases of rheumatic fever had seemed to avert permanent damage to the heart. By & large, however, the Chicago papers proved only that doctors still have much to learn about the new drug. Where long-term administration...