Word: streptomycin
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Universities do not confine their business activities to their nearby environments. Ridgeway describes how some have turned themselves in major beneficiaries of profits from drug discoveries made in their laboratories. Indiana University holds the patents on Crest toothpaste, Rutgers on the drug Streptomycin. The Wisconsin Alumni Research Foundation at the University of Wisconsin provides the university with over $2 million annually, much of it derived from royalties on inventions made in the Foundation labs. (Warfarin, a leading rat poison, is the best known of these...
...antibiotic is good, two must be better, and three even more efficacious." Not so, the Wehrle team found. In a twelve-month study at Los Angeles County General Hospital, every meningitis patient got intravenous ampicillin, a fast-acting form of penicillin, while alternate patients received, in addition, chloramphenicol and streptomycin. There were five deaths among 129 patients on ampicillin alone, but 13 among the 111 who got all three drugs. Using an antibiotic combination is evidently detrimental, perhaps because it interferes with the action of ampicillin...
When it is administered, preventive vaccine is effective, but fresh batches must be kept under refrigeration and administered within two weeks before they go stale-a schedule that is all too easily missed in the war-weary countryside. Massive doses of antibiotics such as streptomycin and chloramphenicol often save those stricken with plague, but without early diagnosis and treatment, the chance of recovery is slim...
...tradition of the patient scientist. Luther Burbank spent 16 years developing an edible cactus for cattle, and during his experiments, by his own estimate, had a million spines painfully pierce his skin. Dr. Selman A. Waksman and his researchers spent four years analyzing 100,000 soil microorganisms before isolating streptomycin. Today, the legendary, lonely experimenter is increasingly giving way to teams working on a variety of crash projects under the "systems approach." Not only team work but the computer is drastically hurrying the pace. But this does not do away with patience; it simply frees it from drudgery and turns...
...research has also given new leads biochemical studies of the mechanism the action of streptomycin...