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Chemotherapy. Doctors used to think that the tough-skinned tubercle bacillus would never succumb to a drug. But promin, diasone, promizole and the brand-new diaminodiphenylsulfone (all sulfa drugs) have showed good results against tuberculosis in guinea pigs, fair promise to human patients (TIME, Dec. 6). Drs. Horton Corwin Hinshaw and William H. Feldman, of the Mayo Clinic, told the Society that tuberculosis will probably succumb to a drug some day but that it is too early to evaluate any drug tried so far. For the sake of Europe, which is suffering a wartime tuberculosis increase, they urged that search...

Author: /time Magazine | Title: Medicine: Tuberculosis Progress | 5/22/1944 | See Source »

...date was announced: Professor George W. Raiziss of Abbott Laboratories reported in Science that disodium formaldehyde sulfoxylate diamino-diphenylsulfone (short name: Diasone) is the best drug yet used to treat guinea pigs newly infected with tuberculosis. It is a sulfa drug which Professor Raiziss says is even better than Promin, another diaminodiphenylsulfone derivative, hitherto the best anti-t.b. drug. Three good points about Diasone: it is only slightly toxic, therefore can be used in fairly large quantities with safety; it is as good as sulfanilamide in curing streptococcus infections in mice; it is almost as good as sulfadiazine...

Author: /time Magazine | Title: Medicine: New T. B. Drug | 11/8/1943 | See Source »

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