Word: naproxen
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That's true also for the use of over-the-counter painkillers like ibuprofen and naproxen, and other non-steroidal anti-inflammatory drugs (NSAIDs) like Celebrex (celecoxib). Guidelines written and published by the American Geriatrics Society warned against using these drugs chronically and at moderate-to-high doses in patients age 75 or older with persistent pain. Citing the many risks of long-term NSAID use, including fatal ulcers and gastrointestinal bleeding, increased risk of heart attack and stroke and dangerous interactions with other drugs commonly prescribed to the elderly, the American Geriatrics Society suggested that seniors try acetaminophen instead...
...Pfizer's move is a dramatic one, but it's also an important one-and not just for Big Pharma's balance sheets. In the wake of the Vioxx withdrawal, many arthritis sufferers have turned to drugs in the ibuprofen and naproxen families, such as Advil and Aleve. But earlier this year the Food and Drug Administration (FDA) announced that those drugs may also carry cardiovascular risks; in any event, for some people they just don't pack the same pain-relieving punch. Others patients are relying on oxycontin and morphine-based medications, which may not endanger the cardiovascular system...
...people in the new study, who will be drawn from the U.S., Canada, Eastern Europe, Australia and South America, will be randomly assigned a regimen of either Celebrex, ibuprofen or naproxen. They will also take aspirin, cholesterol-lowering drugs and other medications appropriate for heart patients, as well as a drug to prevent stomach bleeding, which all three of the painkillers may cause. The four-year study should be sufficient time to reveal what risk, if any, the cox-2s pose, but it could end sooner if one of the medications reveals itself as just too dangerous...
Some ulcers, however, can't be pinned on H. pylori. Instead, they are caused by prescription and over-the-counter anti-inflammatory drugs, such as ibuprofen, aspirin and naproxen, that interfere with the body's mechanism for protecting the stomach lining. The ulcers are particularly common among the elderly, who take a lot of those medicines. Healing begins as soon as you stop taking the drugs...
...NAPROXEN...