Word: michaelson
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Upon further experimentation, Michaelson injected the rat livers with turpentine, a toxic substance. He found that he could thereby select for fibrinogen-producing cells, which fight the poison...
Until now, that is. Harvard Medical School Assistant Professor of Pathology James S. Michaelson has written in a soon-to-be-published paper that Darwinian processes "provide the dominant force in development" and that "cell death is more a cause, than a result, of developmental organization...
Scientists have long wondered how a two-celled zygote develops into a complex organism such as a human. Michaelson's new findings seem to suggest that Darwinian processes of cell selection provide a basis for development. In other words, those cells best fit to survive embryonic development and life as an organism are chosen...
...Michaelson--who also leads a Dunster House seminar on the biology of the diseases of the developing world--began his research with an examination of the immune system and its ability to detect and fight foreign bodies, known as antigens. This highly specific system can destroy these antigens, which invade the body, while leaving a person's cells intact...
Extending this hypothesis, Michaelson began experiments on the liver cells of laboratory rats. Using flourescence microscopy, in which a chemical compound is "tagged" by a flourescent molecule, he showed that different liver cells, or hepatocytes, produced different proteins...