Word: destructive
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Dates: during 1990-1999
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...said if from the start, this team was going to have growing pains at the beginning of the year," coaches Tomassoni said after the Yale loss. "We're not young, but we are inexperienced, and we have that tendency to self-destruct--there's a lot of ability in the locker room, but there are a lot of lessons to be learned...
Thirdly, The Crimson has no authority whatsoever to dictate the terms by which ethnic student organizations should operate. To mandate my resignation The Crimson embraces a paternalistic-style agenda that aims to damage and destruct the efforts of Black students, faculty and administrators. Over the past 15 months, perpetuated attacks have been launched against Rev. Gomes, Dean Archie Epps, Dr. Alien Counter, Mayor Ken Reeves, Professor martin Kilson, and now myself. The Crimson seems to operate under some poorly hidden agenda in which its editors unsuccessfully aim to break others down in an attempt to rebuild its own questionable image...
...when Madonna released her dirty picture book, Sex, she seemed to be moving into self-destruct mode, finishing up her time in the spotlight as a parody of herself. The eroticism she hints at on Bedtime Stories is actually sexier than that of her more wanton songs and videos. Even if a more subdued Madonna is just another pose, it may help her win some of the respect she actually deserves. She is not a great singer, her songs are derivative, her public persona is tawdry. But she can make pretty good records. That's what her dirty little secret...
...latter, they further face a raft of federal definitions that can profoundly affect their economic welfare. The result is painful tensions between individuals and between tribes. Says an Indian activist: Just the question of how much Indian blood an individual possesses has become "a kind of built-in self-destruct button...
...When damage occurs, p53 commands other genes to bring cell division to a halt. If repairs are made, then p53 allows the cell cycle to continue. But in some cases, if the damage is too serious to be patched, p53 activates other genes that cause the cell to self-destruct. Mutations in p53, which have been detected in more than 50% of all human cancers, are thus extremely dangerous. In laboratory cultures, some cancer cells that possess mutant versions of p53 do not die when challenged by antitumor agents, while those that have normal p53 genes go belly...