Word: deference
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Seventy six percent of students offered a place in the College’s Class of 2013 have accepted, the Office of Admissions and Financial Aid told The Crimson on Wednesday in a preliminary release of admissions statistics. This number does not include students who have chosen to defer admission a year, nor does it include students who will later be admitted off the waitlist. Dean of Admissions William R. Fitzsimmons ’67 said this year’s yield could even rise slightly above last year’s 78 percent once waitlist spots are offered, attributing...
...particularly infuriating incident, Rose said that after he repeatedly inquired about a seemingly purposeless investment vehicle, a lawyer informed him that the company was actually set up to help a former employee defer his income to a Cayman Islands entity—thereby avoiding substantial tax payments. He also mentions another instance in his disclosure in which HMC officials adamantly opposed the reporting of a foreign entity—likely because the form used would have been attached to the publicly visible IRS Form 990, exposing Harvard to questioning about its use of offshore accounts...
...scientists looked at patients who chose to initiate ART when their level of CD4 cells - infection-fighting immune cells that HIV uses to replicate and then systematically destroys - ranged between 351 and 500 cells per cubic mm of blood. These patients were compared with those who decided to defer therapy until their counts dipped below 350 cells per cubic mm, the level at which current guidelines recommend starting drug treatment...
...second study, Kitahata's team looked at patients who chose to start ART when their CD4 count was 500 or above and compared them with patients who decided to defer treatment until their CD4 counts dropped below 500 cells. (In a normal, healthy adult, CD4 levels range from 600 to 1,200.) In both studies, the patients deferring treatment were more likely to have died by the 2005 end of the study than were their earlier-treated cohorts. HIV-positive patients beginning therapy at CD4 levels between 351 and 500 cells were 69% more likely to be alive...
...their CD4 counts reached 350 cells or 500 cells, for instance - may have simply been more health-conscious overall and therefore less likely to die, which could have confounded the study's results. Only a randomized and controlled trial in which patients are arbitrarily assigned either to initiate or defer therapy could determine any real benefit of early treatment...