Word: children
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Dates: during 2000-2009
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Since the pandemic began last spring, children have been the hardest hit by H1N1. So far, youngsters have the highest infection, hospitalization and death rates from the pandemic influenza than any other age group, and health officials have targeted those between six months and 24 years old as a priority group for vaccination...
...dose response is substantially better than responses to seasonal flu vaccines of past years," says Terry Nolan of the University of Melbourne, the lead author of the study. That's good news for parents and public health officials, particularly in light of the fact that about half of U.S. children never get their second dose of seasonal flu vaccine. (See how not to get the H1N1...
...study, which involved 370 healthy children ages six months to nine years in Australia, researchers immunized half of the group with two doses of vaccine, each containing 15 micrograms (mcg) of the virus antigen. The other half received two doses containing 30 mcg of the antigen each. In both cases, the second dose was given 21 days after the first. The researchers found that 21 days after receiving only one shot, 92.5% of children in the 15-mcg-dose group and 98% of those receiving the higher dose had generated sufficient antibodies against H1N1...
...results suggest that one shot of the lower-dose vaccine may generate just as many flu antibodies as the two shots U.S. children currently receive, each containing 7.5 mcg of viral antigen. The findings could factor into discussions that health officials have as they make up recommendations for next year's flu season. Having children get immunized only once, rather than twice, may help increase the percentage of kids who are protected against influenza...
Such data will be available only after the flu season ends next spring, at which point researchers can study hospital records of children who were treated for H1N1 infection. Only then can they compare those who received both doses of the vaccine to those who missed their second shot, and see if one or the other group was more likely to come down with...