Word: cellular
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Through an innovative drug screening process designed to find compounds that target cellular energy metabolism, a team of researchers at Harvard-affiliated Massachusetts General Hospital found that the drug Meclizine has the potential to revolutionze the way doctors treat strokes and heart attacks...
...team screened nearly 3,700 compounds—over a third of all FDA-approved drugs—to determine those that could effect a shift from respiration to glycolysis. In the process, researchers discovered that Meclizine can inhibit mitochondrial respiration by shifting cellular metabolism—a promising find for the treatment of heart attacks and strokes...
Lauren Schumacher ’10, a molecular and cellular biology concentrator earning a secondary field in archeology, said she enjoyed the lecture...
...four hunter-gatherers had adaptive genetic variations, called single nucleotide polymorphisms, or SNPs, that may give them a survival advantage in the desert, researchers said: three men had two copies of variants associated with physical prowess and faster sprint performance, and one had a variant for a cellular mechanism that enables a person to retain salt and water - a benefit in a hot, dry climate. Yet another newly discovered genetic trait involved the ability to taste bitter chemicals, which could help hunter-gatherers avoid toxic plants...
...reason for the difference remains only vaguely understood. Environmental factors such as smoking, stress and regular exercise all seem to influence the rate at which our cells age. Now, for the first time, researchers have found a genetic link to cellular aging - a finding that suggests new treatments for a variety of age-related diseases and cancers. (See TIME's Health Checkup "How to Live 100 Years...